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Learn about probes

source:Company News release time:2020-09-30 Article author:小编 Popular:POGO PIN

How much do you know about the probe, what is it for, and what is it made of? I don't know.

The probe is the contact medium for electrical testing, and is a high-end precision electronic hardware component. A probe is a small piece of single-stranded DNA or RNA that is used to detect its complementary nucleic acid sequence. The double-stranded DNA is denatured by heating to become single-stranded, and then labeled with a radioisotope, fluorescent dye or enzyme to become a probe. Phosphorus-32 is usually incorporated into the phosphate group of one of the four nucleotides that make up DNA, while fluorescent dyes and enzymes are covalently linked to the nucleic acid sequence. When the probe is hybridized with the sample, the probe and its complementary nucleic acid sequence are closely linked by hydrogen bonds, and then, the excess probe that has not been hybridized is washed away. Finally, according to the type of label of the probe, autoradiography, fluorescence luminescence, enzyme-linked chemiluminescence and other methods can be used to determine whether or where the sequence to be tested is contained in the sample. Test pin, a probe used to test PCBA. The surface is gold-plated, and there is a high-performance spring with an average life span of 30,000 to 100,000 times inside. The more famous foreign manufacturers are: QA, IDI, UC, Semiprobe, ECT, INGUN, BT, probe materials: W, ReW, CU, A+, the main materials used are W, ReW, normal elasticity, easy to shift , Adhesive gold chips, need multiple cleaning, long wear and tear, and average life. The clean-free needle of A+ material has good elasticity, is not easy to shift during the test, and does not stick to gold chips and does not need to be cleaned, so it has a long life.


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